Kriegstein AR

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• alpha7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex
• Fate plasticity of interneuron specification
• G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation
• Molecular and cellular dynamics of the developing human neocortex
• Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma
• Substructure and maturation of lamina-associated domains in neurons of the developing and adult human brain
• The need for a global effort to attend to human neural organoid and assembloid research
• The new frontier in understanding human and mammalian brain development
• Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease
• Molecular and cellular dynamics of the developing human neocortex at single-cell resolution
• Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularity
• Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact
• Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain
• Protracted neuronal recruitment in the temporal lobes of young children
• Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis
• Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping
• Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations
• LIF signaling regulates outer radial glial to interneuron fate during human cortical development
• Non-muscle myosins control the integrity of cortical radial glial endfeet
• Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy
• Single-cell analysis of prenatal and postnatal human cortical development
• Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus
• A nomenclature consensus for nervous system organoids and assembloids
• Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain
• Nests of dividing neuroblasts sustain interneuron production for the developing human brain
• Tropism of SARS-CoV-2 for human cortical astrocytes
• Zika virus alters centrosome organization to suppress the innate immune response
• Distinct nuclear compartment-associated genome architecture in the developing mammalian brain
• Human intermediate progenitor diversity during cortical development
• Identification of Lipid Heterogeneity and Diversity in the Developing Human Brain
• Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia
• Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes
• A Chromatin Accessibility Atlas of the Developing Human Telencephalon
• Are Organoids Ready for Prime Time?
• Cell-type-specific 3D epigenomes in the developing human cortex
• Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog
• Identification of amygdala-expressed genes associated with autism spectrum disorder
• mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex
• Origins and Proliferative States of Human Oligodendrocyte Precursor Cells
• Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
• SMART-Q: An Integrative Pipeline Quantifying Cell Type-Specific RNA Transcription
• Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
• Immature excitatory neurons develop during adolescence in the human amygdala
• Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex
• Neuroglial stem cell-derived inflammatory pseudotumor (n-SCIPT): clinicopathologic characterization of a novel lesion of the lumbosacral spinal cord and nerve roots following intrathecal allogeneic stem cell intervention
• Neuronal vulnerability and multilineage diversity in multiple sclerosis
• Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing
• Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation
• Single-cell genomics identifies cell type-specific molecular changes in autism
• An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder
• Does Adult Neurogenesis Persist in the Human Hippocampus?
• Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults
• Identification of cell types in a mouse brain single-cell atlas using low sampling coverage
• Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development
• Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity
• Dynamic behaviour of human neuroepithelial cells in the developing forebrain
• Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia
• Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment
• Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex
• The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas
• The use of brain organoids to investigate neural development and disease
• A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA
• Primate Neurons Flex Their Musclin
• Single-cell analysis of long non-coding RNAs in the developing human neocortex
• Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas
• Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development
• Transplanted Human Stem Cell-Derived Interneuron Precursors Mitigate Mouse Bladder Dysfunction and Central Neuropathic Pain after Spinal Cord Injury
• Zika virus cell tropism in the developing human brain and inhibition by azithromycin
• A GABAergic projection from the zona incerta to cortex promotes cortical neuron development
• Molecular identity of human outer radial glia during cortical development
• Neuronal Migration Dynamics in the Developing Ferret Cortex
• The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells
• Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons
• Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells
• Control of outer radial glial stem cell mitosis in the human brain
• Diverse behaviors of outer radial glia in developing ferret and human cortex
• Interneurons from embryonic development to cell-based therapy
• Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex
• Radial glia in the proliferative ventricular zone of the embryonic and adult turtle, Trachemys scripta elegans
• Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex
• The dynamics of neuronal migration
• The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation
• Yoshiki Sasai (1962-2014)
• A high-resolution enhancer atlas of the developing telencephalon
• Cerebral organoids in a dish: progress and prospects
• Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development
• Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex
• Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences
• Use of \"MGE enhancers\" for labeling and selection of embryonic stem cell-derived medial ganglionic eminence (MGE) progenitors and neurons
• OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease
• SnapShot: cortical development
• Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation
• Stem cells in the land of the rising sun: ISSCR 2012
• Blocking early GABA depolarization with bumetanide results in permanent alterations in cortical circuits and sensorimotor gating deficits
• Deriving excitatory neurons of the neocortex from pluripotent stem cells
• Development and evolution of the human neocortex
• Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity
• Connexin 43 mediates the tangential to radial migratory switch in ventrally derived cortical interneurons
• Developmental genetics of vertebrate glial-cell specification
• Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats
• Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear migration in neural stem cells
• Neurogenic radial glia in the outer subventricular zone of human neocortex
• Regenerative medicine: Cell reprogramming gets direct
• Commentary: the prospect of cell-based therapy for epilepsy
• Defining the role of GABA in cortical development
• Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex
• Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis
• GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation
• Gap junctions: multifaceted regulators of embryonic cortical development
• Manipulating midbrain stem cell self-renewal
• Progenitors from the postnatal forebrain subventricular zone differentiate into cerebellar-like interneurons and cerebellar-specific astrocytes upon transplantation
• Cortical neurogenesis: transitioning from advances in the laboratory to cell-based therapies
• Gap junction adhesion is necessary for radial migration in the neocortex
• Neural stem and progenitor cells in cortical development
• Blind patch clamp recordings in embryonic and adult mammalian brain slices
• Estradiol stimulates progenitor cell division in the ventricular and subventricular zones of the embryonic neocortex
• A new era in the ethics of human embryonic stem cell research
• GABA puts the brake on stem cells
• LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages
• Calcium waves propagate through radial glial cells and modulate proliferation in the developing neocortex
• Controlling neuron number: does Numb do the math?
• Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
• Patterns of neuronal migration in the embryonic cortex
• Neurogenic radial glial cells in reptile, rodent and human: from mitosis to migration
• Neurons from radial glia: the consequences of asymmetric inheritance
• Radial glia diversity: a matter of cell fate
• Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors
• Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia
• Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex
• Is there more to GABA than synaptic inhibition?