Kriegstein Lab
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ferroptosis; gene correction; induced pluripotent stem cells; iron chelation; leukodystrophy; myelination; oligodendrocyte; patient models
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation
Pelizaeus-Merzbacher disease (PMD) is an X-linked leukodystrophy caused by mutations in Proteolipid Protein 1 (PLP1), encoding a major …
Hiroko Nobuta
,
Nan Yang
,
Yi Han Ng
,
Samuele G Marro
,
Khalida Sabeur
,
Manideep Chavali
,
John H Stockley
,
David W Killilea
,
Patrick B Walter
,
Chao Zhao
,
Jr, Philip Huie
,
Steven A Goldman
,
Arnold R Kriegstein
,
Robin J M Franklin
,
David H Rowitch
,
Marius Wernig
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