Non-muscle myosins control the integrity of cortical radial glial endfeet.

Abstract

Radial glial cells, the stem cells of the cerebral cortex, extend a long basal fiber that ends in basal endfeet. A new study in PLOS Biology found that non-muscle myosins control basal endfoot integrity to regulate interneuron organization.

Li Wang, PhD

Postdoctoral Scholar

Arnold R Kriegstein, MD, PhD

Professor of Neurology