Cerebral organoids in a dish: progress and prospects

Abstract

A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.

Type
Publication
Cell
Arnold R Kriegstein, MD, PhD
Arnold R Kriegstein, MD, PhD
Professor of Neurology