Manuscript

Substructure and maturation of lamina-associated domains in neurons of the developing and adult human brain.
Approximately 30-40% of the human genome is anchored to the nuclear lamina (NL) through variably sized (10 kb-10 Mb) lamina-associated …
Cite DOI
Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularity.
Diverse retinal ganglion cells (RGCs) transmit distinct visual features from the eye to the brain. Recent studies have categorized RGCs …
Cite DOI
Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease.
Germline genetic architecture of Alzheimer’s disease (AD) indicates microglial mechanisms of disease susceptibility and outcomes. …
Cite DOI
Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping.
The ability to spatially map multiple layers of the omics information over different time points allows for exploring the mechanisms …
Cite DOI
Molecular and cellular dynamics of the developing human neocortex at single-cell resolution.
The development of the human neocortex is a highly dynamic process and involves complex cellular trajectories controlled by …
Cite DOI
Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis.
The nuclear genome is spatially organized into a three-dimensional (3D) architecture by physical association of large chromosomal …
Cite DOI
Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping.
The ability to spatially map multiple layers of the omics information over different time points allows for exploring the mechanisms …
Cite DOI
Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.
Duplication 15q (dup15q) syndrome is the most common genetic cause of autism spectrum disorder (ASD). Due to a higher genetic and …
Cite DOI
Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) readily infects a variety of cell types impacting the function of …
Cite DOI