2

The use of brain organoids to investigate neural development and disease
Understanding the development and dysfunction of the human brain is a major goal of neurobiology. Much of our current understanding of …
Cite
Dynamic behaviour of human neuroepithelial cells in the developing forebrain
To understand how diverse progenitor cells contribute to human neocortex development, we examined forebrain progenitor behaviour using …
Cite
Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia
Classical lissencephaly is a genetic neurological disorder associated with mental retardation and intractable epilepsy, and …
Cite
Primate Neurons Flex Their Musclin
Sensory experience evokes long-lasting changes in neural circuits through activity-dependent gene expression. Ataman et al. (2016) …
Cite
Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas
Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain tumor. Epidermal growth factor (EGF) and …
Cite
Zika virus cell tropism in the developing human brain and inhibition by azithromycin
The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development constitute a global health emergency. …
Cite
Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development
The classic view of cortical development, embodied in the radial unit hypothesis, highlights the ventricular radial glia (vRG) scaffold …
Cite
Transplanted Human Stem Cell-Derived Interneuron Precursors Mitigate Mouse Bladder Dysfunction and Central Neuropathic Pain after Spinal Cord Injury
Neuropathic pain and bladder dysfunction represent significant quality-of-life issues for many spinal cord injury patients. Loss of …
Cite
A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA
Long non-coding RNAs (lncRNAs) are a diverse and poorly conserved category of transcripts that have expanded greatly in primates, …
Cite
Single-cell analysis of long non-coding RNAs in the developing human neocortex
BACKGROUND: Long non-coding RNAs (lncRNAs) comprise a diverse class of transcripts that can regulate molecular and cellular processes …
Cite