Kriegstein Lab
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Turtle cortical neurons survive glutamate exposures that are lethal to mammalian neurons
Glutamate is an excitatory neurotransmitter in turtle and mammalian cortex. In high concentrations it is toxic to mammalian neurons and …
A M Wilson
,
A R Kriegstein
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Endogenous neurotransmitter activates N-methyl-D-aspartate receptors on differentiating neurons in embryonic cortex
Before synapses form in embryonic turtle cerebral cortex, an endogenous neurotransmitter activates N-methyl-D-aspartate (NMDA) channels …
M G Blanton
,
J J Lo Turco
,
A R Kriegstein
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Differential activation of glutamate receptors by spontaneously released transmitter in slices of neocortex
Whole-cell recordings were made from neurons in neocortical brain slices in order to characterize excitatory synaptic currents mediated …
J J LoTurco
,
I Mody
,
A R Kriegstein
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Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex
We describe methods for obtaining stable, whole-cell recordings from neurons in brain hemispheres from turtles and in brain slices from …
M G Blanton
,
J J Lo Turco
,
A R Kriegstein
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The development of bicuculline-induced epileptiform discharges in embryonic turtle cortex
The appearance of bicuculline-induced epileptiform discharges was studied in embryonic turtle cortex using extracellular recording …
J M Shen
,
A R Kriegstein
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Development of GABA responsiveness in embryonic turtle cortical neurons
The whole-cell patch-clamp method was used to study the development of functional GABA receptors in cortical neurons dissociated from …
J M Shen
,
J R Huguenard
,
A R Kriegstein
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Quantitative autoradiography of muscarinic and benzodiazepine receptors in the forebrain of the turtle, Pseudemys scripta
The distribution of muscarinic and benzodiazepine receptors was investigated in the turtle forebrain by the technique of in vitro …
J R Schlegel
,
A R Kriegstein
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Cellular and synaptic physiology and epileptogenesis of developing rat neocortical neurons in vitro
The cellular and synaptic physiology of developing rat neocortical neurons was studied using the in vitro slice method. Rats aged 1-28 …
A R Kriegstein
,
T Suppes
,
D a Prince
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Synaptic responses of cortical pyramidal neurons to light stimulation in the isolated turtle visual system
The resistance of the turtle brain to hypoxic injury permits a unique in vitro preparation in which the organization and function of …
A R Kriegstein
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Evidence for the inhibitory neurotransmitter gamma-aminobutyric acid in aspiny and sparsely spiny nonpyramidal neurons of the turtle dorsal cortex
In order to learn more about the anatomical substrate for gamma-aminobutyric acid (GABA)-mediated inhibition in cortical structures, …
M G Blanton
,
J M Shen
,
A R Kriegstein
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