Kriegstein Lab
Kriegstein Lab
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Cortical neurogenesis and its disorders
Proliferative cells lining the cerebral ventricles generate all of the phenotypically diverse neurons of the adult cortex. Recent …
A R Kriegstein
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GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis
We have found that, during the early stages of cortical neurogenesis, both GABA and glutamate depolarize cells in the ventricular zone …
J J LoTurco
,
D F Owens
,
M J Heath
,
M B Davis
,
A R Kriegstein
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Properties of amino acid neurotransmitter receptors of embryonic cortical neurons when activated by exogenous and endogenous agonists
The properties of receptors for amino acid neurotransmitters expressed by developing cortical neurons were studied with the use of …
M G Blanton
,
A R Kriegstein
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Abnormal action-potential bursts and synchronized, GABA-mediated inhibitory potentials in an in vitro model of focal epilepsy
Focal, freeze-induced lesions were made in isolated hemispheres of turtle cerebral cortex in vitro, permitting the investigation of …
M D Troyer
,
M G Blanton
,
A R Kriegstein
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Norepinephrine activates potassium conductance in neurons of the turtle cerebral cortex
Whole-cell voltage and current clamp recordings were obtained from cortical neurons of the pond turtle, Pseudemys scripta elegans. …
K J Blanton
,
A R Kriegstein
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Spontaneous action potential activity and synaptic currents in the embryonic turtle cerebral cortex
We used loose-patch and whole-cell recording techniques to study the development of spontaneous action potential activity and …
M G Blanton
,
A R Kriegstein
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Appearance of putative amino acid neurotransmitters during differentiation of neurons in embryonic turtle cerebral cortex
Pyramidal and nonpyramidal neurons can be recognized early in the development of the cerebral cortex in both reptiles and mammals, and …
M G Blanton
,
A R Kriegstein
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Morphological differentiation of distinct neuronal classes in embryonic turtle cerebral cortex
As a starting point for understanding the development of the cerebral cortex in reptiles and for determining how reptilian cortical …
M G Blanton
,
A R Kriegstein
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Clusters of coupled neuroblasts in embryonic neocortex
The neocortex of the brain develops from a simple germinal layer into a complex multilayer structure. To investigate cellular …
J J Lo Turco
,
A R Kriegstein
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Initial expression and endogenous activation of NMDA channels in early neocortical development
We have made patch-clamp recordings from slices of fetal and postnatal rat neocortex in order to study the initial expression and …
J J LoTurco
,
M G Blanton
,
A R Kriegstein
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