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Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia
The embryonic ventricular zone (VZ) of the cerebral cortex contains migrating neurons, radial glial cells, and a large population of …
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GABA may act as a self-limiting trophic factor at developing synapses
Early in development, synapses with glycine or gamma-aminobutyric acid (GABA)-gated chloride channels exhibit the ability to depolarize …
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Neurons derived from radial glial cells establish radial units in neocortex
The neocortex of the adult brain consists of neurons and glia that are generated by precursor cells of the embryonic ventricular zone. …
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Maturation of channels and receptors: consequences for excitability
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Transient actions of neurotransmitters during neocortical development
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An excitatory GABAergic plexus in developing neocortical layer 1
Layer 1 of the developing rodent somatosensory cortex contains a dense, transient GABAergic fiber plexus. Axons arising from the zona …
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Extrinsic GABAergic innervation of developing neocortical layer 1 in organotypic slice co-cultures
Afferents from the zona incerta (ZI) of the ventral thalamus contribute to the dense, transient gamma-aminobutyric acid (GABA)ergic …
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Calcium dynamics of neocortical ventricular zone cells
Cell-cell signaling within the neocortical ventricular zone (VZ) has been shown to influence the proliferation of VZ precursor cells …
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Leukoencephalopathy and raised brain lactate from heroin vapor inhalation (``chasing the dragon'')
BACKGROUND: Inhalation of heated heroin vapor (``chasing the dragon’’), which is gaining popularity among drug users …
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Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations
Oscillations in intracellular free calcium concentration (Ca(2+)) occur spontaneously in immature neurons of the developing cerebral …
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