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Controlling neuron number: does Numb do the math?
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Patterns of neuronal migration in the embryonic cortex
Real-time imaging of migrating neurons has changed our understanding of how newborn neurons reach their final positions in the …
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Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
Precise patterns of cell division and migration are crucial to transform the neuroepithelium of the embryonic forebrain into the adult …
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Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors
Glycine and gamma-aminobutyric acid, type A (GABA(A)) receptors are members of the ligand-gated ion channel superfamily that mediate …
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Radial glia diversity: a matter of cell fate
Early in development of the central nervous system, radial glial cells arise from the neuroepithelial cells lining the ventricles …
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Neurogenic radial glial cells in reptile, rodent and human: from mitosis to migration
Radial glial cells play at least two crucial roles in cortical development: neuronal production in the ventricular zone (VZ) and the …
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Neurons from radial glia: the consequences of asymmetric inheritance
Recent work suggests that radial glial cells represent many, if not most, of the neuronal progenitors in the developing cortex. …
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Developmental neurotransmitters?
Previous studies support an early role for neurotransmitter signaling before synaptogenesis, but puzzlingly, a neurological phenotype …
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Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex
PURPOSE: Cortical dysplasia (CD) is associated with epilepsy in both the pediatric and adult populations. The mechanism underlying …
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Is there more to GABA than synaptic inhibition?
In the mature brain, GABA (gamma-aminobutyric acid) functions primarily as an inhibitory neurotransmitter. But it can also act as a …
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